Article

A Vascular Dissection and Rupture Linked Metabolite Acts Via BLT2 Receptor

2024-02-16

Abstract excerpt

<h4>BACKGROUND</h4> Thoracic aortic dissection (TAD) is a life-threatening vascular disease that requires effective drug treatment to prevent progression and rupture. Because arachidonic acid metabolism is involved in inflammation and vascular homeostasis, we investigated the roles of arachidonic acid metabolites in TAD pathogenesis and their utility as therapeutic targets. <h4>METHODS</h4> Serum metabolomics an...

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Literature Corpus work: 508daa3e-fd4e-5f5a-9e16-e94ba8b3379c
DOI: 10.1101/2024.02.15.580482

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