Article

Family-based association analysis identifies variance-controlling loci without confounding by genotype-environment correlations

2017-08-11

Abstract excerpt

The propensity of a trait to vary within a population may have evolutionary, ecological, or clinical significance. In the present study we deploy sibling models to offer a novel and unbiased way to ascertain loci associated with the extent to which phenotypes vary (variance-controlling quantitative trait loci, or vQTLs). Previous methods for vQTL-mapping either exclude genetically related individuals or treat gene...

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Literature Corpus work: 1c7395b4-02ee-507c-913d-a0f1fc87b10a
DOI: 10.1101/175596

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