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Article

Phenotypic covariance across the entire spectrum of relatedness for 86 billion pairs of individuals.

Nature communications - 16 Feb 2021

Kemper Kathryn E, Yengo Loic, Zheng Zhili, Abdellaoui Abdel, Keller Matthew C, Goddard Michael E, Wray Naomi R, Yang Jian, Visscher Peter M

Abstract excerpt

Attributing the similarity between individuals to genetic and non-genetic factors is central to genetic analyses. In this paper we use the genomic relationship ([Formula: see text]) among 417,060 individuals to investigate the phenotypic covariance between pairs of individuals for 32 traits across the spectrum of relatedness, from unrelated pairs through to identical twins. We find linear relationships between...

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Identifiers

PMID: 33594080
DOI: 10.1038/s41467-021-21283-4
PMCID: PMC7886899

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