Article
A sibling method for identifying vQTLs.
PloS one - 1 Jan 2018
Conley Dalton, Johnson Rebecca, Domingue Ben, Dawes Christopher, Boardman Jason, Siegal Mark L
Abstract excerpt
The propensity of a trait to vary within a population may have evolutionary, ecological, or clinical significance. In the present study we deploy sibling models to offer a novel and unbiased way to ascertain loci associated with the extent to which phenotypes vary (variance-controlling quantitative trait loci, or vQTLs). Previous methods for vQTL-mapping either exclude genetically related individuals or treat...
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