Article
A family-based joint test for mean and variance heterogeneity for quantitative traits.
Annals of human genetics - 1 Jan 2015
Cao Ying, Maxwell Taylor J, Wei Peng
Abstract excerpt
Traditional quantitative trait locus (QTL) analysis focuses on identifying loci associated with mean heterogeneity. Recent research has discovered loci associated with phenotype variance heterogeneity (vQTL), which is important in studying genetic association with complex traits, especially for identifying gene-gene and gene-environment interactions. While several tests have been proposed to detect vQTL for...
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