Article

Cancer-induced Nerve Injury Unveils a Sympathetic-to-Sensory Nerve Axis in Head and Neck Cancer

2025-09-19

Abstract excerpt

Oral squamous cell carcinoma (OSCC) is one of the most painful cancers, with patients frequently reporting spontaneous, neuropathic-like pain. While sympathetic and sensory nerves have been individually implicated in cancer progression, whether and how these systems interact to drive pain and tumor growth has remained unclear. Here, we integrate prospective human data with reverse-translational mouse models to rev...

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Literature Corpus work: 9203d098-eefc-50b9-9871-03e0b70e0c65
DOI: 10.1101/2025.09.19.677339

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