Article

Sex-dependent Differences in the Genomic Profile of Lingual Sensory Neurons in Naïve and Tongue-Tumor Bearing Mice

2023-01-17

Abstract excerpt

Mechanisms of sex-dependent orofacial pain are widely understudied. A significant gap in knowledge exists about comprehensive regulation of tissue-specific trigeminal sensory neurons in diseased state of both sexes. Using RNA sequencing of FACS sorted retro-labeled sensory neurons innervating tongue tissue, we determined changes in transcriptomic profiles in males and female mice under naïve as well as tongue-tumo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5baeaa2a-b04d-559e-bb5b-9ff10c7b8ec4
DOI: 10.1101/2023.01.14.524011

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sex-dependent Differences in the Genomic Profile of Lingual Sensory Neurons in Naïve and Tongue-Tumor Bearing MiceDOI 10.1101/2023.01.14.524011Read

Transcriptomic sex differences in sensory neuronal populations of miceSemantic proximity Read

Differential transcriptional profiles of vagal sensory neurons in female and male miceSemantic proximity Read

Understanding Painful versus Non-Painful Dental Pain in Male and Female Patients: A Transcriptomic Analysis of Human BiopsiesSemantic proximity Read

RNA Profiling of Neuropathic Pain-Associated Human DRGs Reveal Sex-differences in Neuro-immune Interactions Promoting PainSemantic proximity Read

RNA profiling of human dorsal root ganglia reveals sex differences in mechanisms promoting neuropathic painSemantic proximity Read

Cancer-induced Nerve Injury Unveils a Sympathetic-to-Sensory Nerve Axis in Head and Neck CancerSemantic proximity Read

Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptorsSemantic proximity Read

Spatial transcriptomics reveals unique molecular fingerprints of human nociceptorsSemantic proximity Read

Investigation of cellular and molecular changes linked with neuropathic pain in healthy and injured human trigeminal nervesSemantic proximity Read

The pathophysiology of trigeminal neuralgia: a molecular reviewSemantic proximity Read

Single-nucleus transcriptomic analysis of human dorsal root ganglion neuronsSemantic proximity Read

Single nucleus transcriptomic analysis of human dorsal root ganglion neuronsSemantic proximity Read