Article

Primate-Specific LINC03040 Drives MASH Fibrosis via a Myeloid-Dependent Immuno-Metabolic Axis

2026-02-09

Abstract excerpt

<title>Abstract</title> <p> Background While the recent approval of resmetirom marks a historic milestone in MASH therapy, the effective reversal of established cirrhosis (F4) remains a major unmet clinical need. A critical bottleneck in developing anti-fibrotic drugs for this advanced stage is the profound translational gap between murine models and human immunopathology, particularly regarding species-specifi...

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Literature Corpus work: 1c682606-a086-5fca-90dc-6d6daca15fd5
DOI: 10.21203/rs.3.rs-8780157/v1

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