Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Decoding liver fibrogenesis with single-cell technologies

29 Sept 2022

Abstract excerpt

Liver fibrogenesis is a highly dynamic and complex process that drives the progression of chronic liver disease toward liver failure and end-stage liver diseases. Despite decades of intense studies, the cellular and molecular mechanisms underlying liver fibrogenesis remain elusive, and no approved therapies to treat liver fibrosis are currently available. The rapid development of single-cell RNA sequencing...

Topics

Join the communities discussing this publication.

Liver Disease Diagnosis and Treatment
Liver physiology and pathology
Single-cell and spatial transcriptomics

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39872749
DOI: 10.1093/lifemedi/lnac040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Decoding liver fibrogenesis with single-cell technologiesPMID 39872749Read ↗

Single-cell RNA sequencing advances in revealing the development and progression of MASH: the identifications and interactions of non-parenchymal cellsSemantic proximity Read ↗

Single-cell RNA transcriptome landscape of hepatocytes and non-parenchymal cells in healthy and NAFLD mouse liverSemantic proximity Read ↗

Single‐cell RNA sequencing reveals the heterogeneity and intercellular communication of hepatic stellate cells and macrophages during liver fibrosisSemantic proximity Read ↗

Understanding the cellular interactome of non-alcoholic fatty liver diseaseSemantic proximity Read ↗

Single-cell and bulk transcriptomics of the liver reveals potential targets of NASH with fibrosisSemantic proximity Read ↗

A comprehensive molecular atlas of the cell types in the mouse liverSemantic proximity Read ↗

Resolving the fibrotic niche of human liver cirrhosis using single-cell transcriptomicsSemantic proximity Read ↗

A Single Cell Gene Expression Atlas of 28 Human LiversSemantic proximity Read ↗

Single-cell transcriptomic profiling of healthy and fibrotic adult zebrafish liver reveals conserved cell identities and stellate cell activation phenotypes with human liverSemantic proximity Read ↗

Found in translation—Fibrosis in metabolic dysfunction–associated steatohepatitis (MASH)Semantic proximity Read ↗

Transcriptome analysis of liver sinusoidal endothelial cells in patients with liver cirrhosisSemantic proximity Read ↗

Key genes in the liver fibrosis process are mined based on single-cell transcriptomicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.