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Article

A prognostic molecular signature of hepatic steatosis is spatially heterogeneous and dynamic in human liver

2024-01-27

Abstract excerpt

<h4>SUMMARY</h4> Metabolic dysfunction-associated steatotic liver disease (MASLD) prevalence is increasing in parallel with an obesity pandemic, calling for novel strategies for prevention and treatment. We defined a circulating proteome of human MASLD across ≈7000 proteins in ≈5000 individuals from diverse, at-risk populations across the metabolic health spectrum, demonstrating reproducible diagnostic performance...

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Literature Corpus work
b644af69-eba9-5a3f-be8c-f10c028e7dd7
DOI
10.1101/2024.01.26.24301828
Open publication

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A prognostic molecular signature of hepatic steatosis is spatially heterogeneous and dynamic in human liverDOI 10.1101/2024.01.26.24301828
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