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HIV inhibits Warburg metabolism in human macrophages infected with Mycobacterium tuberculosis

2025-05-11

Abstract excerpt

Tuberculosis (TB)-associated mortality remains disproportionately high among people living with HIV (PLWH), with macrophage dysfunction representing a key mechanism of impaired host defence against Mycobacterium tuberculosis (Mtb) infection. Using the U1 chronically HIV-infected macrophage cell line model coupled with primary human monocyte-derived macrophages (MDMs) exposed to HIV-1 gp120, we systematically chara...

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Identifiers and source

Literature Corpus work
1c3a570f-59f8-51d0-b632-01790664afbe
DOI
10.1101/2025.05.09.653039
Open publication

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HIV inhibits Warburg metabolism in human macrophages infected with Mycobacterium tuberculosisDOI 10.1101/2025.05.09.653039
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