Article

Dissecting the roles of Haspin and VRK1 in Histone H3 threonine-3 phosphorylation during mitosis

2021-09-07

Abstract excerpt

Protein kinases that phosphorylate histones are ideally-placed to influence the behavior of chromosomes during cell division. Indeed, a number of conserved histone phosphorylation events occur prominently during mitosis and meiosis in most eukaryotes, including on histone H3 at threonine-3 (H3T3ph). At least two kinases, Haspin and VRK1 (NHK-1/ballchen in Drosophila ), have been proposed to carry out this modific...

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Literature Corpus work: 1b92bcc2-b9eb-5790-b4d3-47cdf4554461
DOI: 10.1101/2021.09.07.459242

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