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Genetic analysis of <i>C. elegans</i> Haspin-like genes shows that <i>hasp-1</i> plays multiple roles in the germline

2022-02-13

Abstract excerpt

Haspin is a histone kinase that promotes error-free chromosome segregation by recruiting the Chromosomal Passenger Complex (CPC) to mitotic and meiotic chromosomes. Haspin remains less well studied than other M-phase kinases and the models explaining Haspin function have been developed primarily in mitotic cells. Here, we generate new mutations in the C. elegans Haspin homologs hasp-1 and hasp-2 and characteriz...

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Literature Corpus work: bf1ee05a-2c93-5e42-8b1f-6109bd1c6353
DOI: 10.1101/2022.02.12.480216

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