Article

Genetic Risk and Resilience for Schizophrenia Stratified by Perinatal Gene Expression Predict Adult Cognitive Performance

2026-05-19

Abstract excerpt

Genetic risk for schizophrenia (SCZ) has been linked to cognitive performance before the onset age. We examined how SCZ-related polygenic risk and resilience variants, and their co-expression patterns in the human brain, were associated with cognitive abilities across development in 16,520 non-psychiatric European and African ancestry children and adults. SCZ risk showed significant negative associations with spat...

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Literature Corpus work: 1b75f145-329b-5c7f-b8a1-918b2e5887c0
DOI: 10.64898/2026.05.19.726222

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