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Article

Dissecting Schizophrenia Biology Using Pleiotropy With Cognitive Genomics.

Biological psychiatry - 1 Nov 2025

Bhattacharyya Upasana, John Jibin, Lencz Todd, Lam Max

Abstract excerpt

BACKGROUND: Given the increasingly large number of loci discovered by psychiatric genome-wide association studies (GWASs), specification of the key biological pathways that underlie these loci has become a priority for the field. We have previously leveraged the pleiotropic genetic relationships between schizophrenia (SCZ) and 2 cognitive phenotypes (educational attainment and cognitive task performance) to...

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Identifiers

PMID: 39993652
DOI: 10.1016/j.biopsych.2025.02.890
PMCID: PMC12353775

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