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Article

Polygenic risk for schizophrenia is associated with cognitive change between childhood and old age.

Biological psychiatry - 15 May 2013

McIntosh Andrew M, Gow Alan, Luciano Michelle, Davies Gail, Liewald David C, Harris Sarah E, Corley Janie, Hall Jeremy, Starr John M, Porteous David J, Tenesa Albert, Visscher Peter M, Deary Ian J

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWAS) have shown a polygenic component to the risk of schizophrenia. The disorder is associated with impairments in general cognitive ability that also have a substantial genetic contribution. No study has determined whether cognitive impairments can be attributed to schizophrenia's polygenic architecture using data from GWAS. METHODS: Members of the Lothian Birth...

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Identifiers

PMID: 23419543
DOI: 10.1016/j.biopsych.2013.01.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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