Article
Common genetic variation and schizophrenia polygenic risk influence neurocognitive performance in young adulthood.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2015
Hatzimanolis Alex, Bhatnagar Pallav, Moes Anna, Wang Ruihua, Roussos Panos, Bitsios Panos, Stefanis Costas N, Pulver Ann E, Arking Dan E, Smyrnis Nikolaos, Stefanis Nicholas C, Avramopoulos Dimitrios
Abstract excerpt
Neurocognitive abilities constitute complex traits with considerable heritability. Impaired neurocognition is typically observed in schizophrenia (SZ), whereas convergent evidence has shown shared genetic determinants between neurocognition and SZ. Here, we report a genome-wide association study (GWAS) on neuropsychological and oculomotor traits, linked to SZ, in a general population sample of healthy young males...
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