Article
Rethinking schizophrenia: insights from genomics and implications for research.
Molecular psychiatry - 1 Oct 2026
Owen Michael J, O'Donovan Michael C
Abstract excerpt
Recent genomic research, considered in the wider context of knowledge from outside genomics, provides significant conceptual insights into the aetiology and pathogenesis of schizophrenia. The evidence indicates that genetic risk is expressed across the lifespan, from foetal development through to adulthood, and involves multiple neuronal types and brain regions. Schizophrenia appears to be primarily a neuronal...
Read the complete abstract on PubMedTopics
- Humans
- Schizophrenia
- Genetic Predisposition to Disease
- Genomics
- Neurodevelopment
- Brain
- Animals
