Article

Altered Glia-Neuron Communication in Alzheimer’s Disease Affects WNT, p53, and NFkB Signaling Determined by snRNA-seq

2023-12-01

Abstract excerpt

<h4>Background</h4> Alzheimer’s disease is the most common cause of dementia and is characterized by amyloid-β plaques, tau neurofibrillary tangles, and neuronal loss. Although neuronal loss is a primary hallmark of Alzheimer’s disease, it is known that non-neuronal cell populations are ultimately responsible for maintaining brain homeostasis and neuronal health through neuron-glia and glial cell crosstalk. Many...

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Literature Corpus work: 1b72d219-4fcf-59dc-b785-7048e98fbb7b
DOI: 10.1101/2023.11.29.569304

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