Article

The glutathione S-transferase Gstt1 is a robust driver of survival and dissemination in metastases

2022-09-13

Abstract excerpt

<h4>ABSTRACT</h4> Identifying adaptive mechanisms of metastatic cancer cells remains an elusive question in the treatment of metastatic disease, particularly in pancreatic cancer (PDA), where the majority of patients present with metastatic lesions at the time of diagnosis. A loss-of-function shRNA targeted screen in metastatic-derived cells identified Gstt1 , a member of the glutathione S-transferase superfamil...

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Literature Corpus work: 1b3d84f0-0850-584c-8de6-8223af004b02
DOI: 10.1101/2022.09.10.507413

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