Article
Death-from-cancer signatures and stem cell contribution to metastatic cancer.
Cell cycle (Georgetown, Tex.) - 1 Sept 2005
Glinsky Gennadi V
Abstract excerpt
Genome-wide expression profiling studies reveal a transcriptionally distinct sub-type of human solid tumors with a marked propensity toward metastatic dissemination, highly malignant clinical behavior, and poor therapy outcome in cancer patients diagnosed with the early stage carcinomas of various origins. This sub-set of tumors acquires full metastatic potential, including an emergence and seeding of potent...
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