Article

Addiction-associated genetic variants implicate brain cell type- and region-specific cis-regulatory elements in addiction neurobiology

2020-09-30

Abstract excerpt

<h4>ABSTRACT</h4> Recent large genome-wide association studies (GWAS) have identified multiple confident risk loci linked to addiction-associated behavioral traits. Genetic variants linked to addiction-associated traits lie largely in non-coding regions of the genome, likely disrupting cis-regulatory element (CRE) function. CREs tend to be highly cell type-specific and may contribute to the functional development...

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Literature Corpus work: 1a6c18c3-6155-5c79-b5d7-a81c85203c8c
DOI: 10.1101/2020.09.29.318329

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