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Article

"Higher order" addiction molecular genetics: convergent data from genome-wide association in humans and mice.

Biochemical pharmacology - 1 Jan 2008

Uhl George R, Drgon Tomas, Johnson Catherine, Fatusin Oluwatosin O, Liu Qing-Rong, Contoreggi Carlo, Li Chuan-Yun, Buck Kari, Crabbe John

Abstract excerpt

Family, adoption and twin data each support substantial heritability for addictions. Most of this heritable influence is not substance-specific. The overlapping genetic vulnerability for developing dependence on a variety of addictive substances suggests large roles for "higher order" pharamacogenomics in addiction molecular genetics. We and others have now completed genome-wide association (GWA) studies of DNAs...

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Identifiers

PMID: 17764662
DOI: 10.1016/j.bcp.2007.06.042
PMCID: PMC3282179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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