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Article

Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits.

Molecular psychiatry - 1 Jul 2022

Sey Nancy Y A, Hu Benxia, Iskhakova Marina, Lee Sool, Sun Huaigu, Shokrian Neda, Ben Hutta Gabriella, Marks Jesse A, Quach Bryan C, Johnson Eric O, Hancock Dana B, Akbarian Schahram, Won Hyejung

Abstract excerpt

Cigarette smoking and alcohol use are among the most prevalent substances used worldwide and account for a substantial proportion of preventable morbidity and mortality, underscoring the public health significance of understanding their etiology. Genome-wide association studies (GWAS) have successfully identified genetic variants associated with cigarette smoking and alcohol use traits. However, the vast majority...

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Identifiers

PMID: 35422469
DOI: 10.1038/s41380-022-01558-y
PMCID: PMC9853312

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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