Article
Alteration of the bioenergetic phenotype of mitochondria is a hallmark of breast, gastric, lung and oesophageal cancer.
The Biochemical journal - 15 Feb 2004
Isidoro Antonio, Martínez Marta, Fernández Pedro L, Ortega Alvaro D, Santamaría Gema, Chamorro Margarita, Reed John C, Cuezva José M
Abstract excerpt
Recent findings indicate that the expression of the beta-catalytic subunit of the mitochondrial H+-ATP synthase (beta-F1-ATPase) is depressed in liver, kidney and colon carcinomas, providing further a bioenergetic signature of cancer that is associated with patient survival. In the present study, we performed an analysis of mitochondrial and glycolytic protein markers in breast, gastric and prostate...
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