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Article

Individual-specific variation in the respiratory activities of HMECs and their bioenergetic response to IGF1 and TNFα.

Journal of cellular physiology - 1 Oct 2017

Schneider Sallie S, Henchey Elizabeth M, Sultana Nazneen, Morin Stephanie M, Jerry D Joseph, Makari-Judson Grace, Crisi Giovanna M, Arenas Richard B, Johnson Melissa, Mason Holly S, Yadava Nagendra

Abstract excerpt

Metabolic reprograming is a hallmark of cancer cells. However, the roles of pre-existing differences in normal cells metabolism toward cancer risk is not known. In order to assess pre-existing variations in normal cell metabolism, we have quantified the inter-individual variation in oxidative metabolism of normal primary human mammary epithelial cells (HMECs). We then assessed their response to selected cytokines...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Insulin-Like Growth Factor I

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Source

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Identifiers

PMID: 28369883
DOI: 10.1002/jcp.25932
PMCID: PMC5518214

Genes

IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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