Article

The Nutrigenomic Landscape of Mitochondrial Metabolism: Targeting Growth Factor Signaling in Translational Oncology

2026-02-10

Abstract excerpt

<h4>Background: </h4> The metabolic flexibility of cancer cells, primarily driven by mitochondrial reprogramming and constitutive Growth Factor Signaling (GFS), remains a formidable barrier to therapeutic success. While the “Warburg Effect” was traditionally viewed as a consequence of irreversible mitochondrial defects, modern evidence suggests a proactive “metabolic hijacking” where growth factors drive mitochond...

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Literature Corpus work: a2736106-b8bc-5ff1-b2ca-5b277e0dfc6d
DOI: 10.20944/preprints202602.0737.v1

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