Article

Non-canonical hepatic androgen receptor mediates glucagon sensitivity in female mice through the PGC1α/ERRα/mitochondria axis

2023-11-04

Abstract excerpt

The hormone glucagon plays a crucial role in maintaining normal blood glucose levels and has recently been found to promote liver lipid catabolism in both clinical and basic research studies. However, the mechanisms by which glucagon signaling synchronizes glucose and lipid metabolism in the liver remain poorly understood. Here, we report that hepatic androgen receptor (AR) functions as a critical mediator of gluc...

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Literature Corpus work: 1a58cc46-7f31-5f29-b75d-f4e5f9e5a261
DOI: 10.1101/2023.11.02.565247

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Non-canonical hepatic androgen receptor mediates glucagon sensitivity in female mice through the PGC1α/ERRα/mitochondria axisDOI 10.1101/2023.11.02.565247Read

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