Article

Hepatocyte ERα orchestrates sex-specific liver adaptation to fasting and feeding states

2025-12-09

Abstract excerpt

<h4>ABSTRACT</h4> Sex differences in hepatic physiology are thought to influence individual susceptibility to chronic liver diseases including Metabolic-Associated Steatotic Liver Disease (MALSD). Previous studies demonstrated the central contribution of estrogens which primarily influence liver biology through the activation of Estrogen Receptor alpha (ERα). However, how ERα signaling in hepatocyte modulates liv...

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Literature Corpus work: db5e2966-4225-587f-a4fc-3c09ec3650fc
DOI: 10.64898/2025.12.05.692559

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