Article

Leveraging Gene Co-expression Patterns to Infer Trait-Relevant Tissues in Genome-wide Association Studies

2019-07-17

Abstract excerpt

Genome-wide association studies (GWASs) have identified many SNPs associated with various common diseases. Understanding the biological functions of these identified SNP associations requires identifying disease/trait relevant tissues or cell types. Here, we develop a network method, CoCoNet, to facilitate the identification of trait-relevant tissues or cell types. Different from existing approaches, CoCoNet incor...

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Literature Corpus work: 1a1d2f23-ecb2-516e-b5c4-96cb6932d069
DOI: 10.1101/705129

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