Article
Simultaneous inference of phenotype-associated genes and relevant tissues from GWAS data via Bayesian integration of multiple tissue-specific gene networks.
Journal of molecular cell biology - 1 Dec 2017
Wu Mengmeng, Lin Zhixiang, Ma Shining, Chen Ting, Jiang Rui, Wong Wing Hung
Abstract excerpt
Although genome-wide association studies (GWAS) have successfully identified thousands of genomic loci associated with hundreds of complex traits in the past decade, the debate about such problems as missing heritability and weak interpretability has been appealing for effective computational methods to facilitate the advanced analysis of the vast volume of existing and anticipated genetic data. Towards this...
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