Article

Competition of Charge-Mediated and Specific Binding by Peptide-Tagged Cationic Liposome–DNA Nanoparticles <i>In Vitro</i> and <i>In Vivo</i>

2017-06-26

Abstract excerpt

Cationic liposome–nucleic acid (CL–NA) complexes, which form spontaneously, are a highly modular gene delivery system. These complexes can be sterically stabilized via PEGylation [PEG: poly(ethylene glycol)] into nanoparticles (NPs) and targeted to specific tissues and cell types via the conjugation of an affinity ligand. However, there are currently no guidelines on how to effectively navigate the large space of...

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Literature Corpus work: 19dae5d0-abab-536a-9e25-c42e22cd9200
DOI: 10.1101/156166

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