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Article

Rv1985c-Driven Transcriptional Network Rewiring Underlies Lineage-Specific Phenotypes in <i>Mycobacterium tuberculosis</i>

2020-02-14

Abstract excerpt

<h4>Summary</h4> The Mycobacterium tuberculosis (Mtb) complex includes ten phylogenetically distinct human-adapted lineages with varying geographical distributions and pathogenicity. Lineage 1 (L1) is associated with low virulence, while Lineage 2 (L2) is linked to hyper-virulence, increased transmission, and drug resistance. We performed multi-layer comparative analyses integrating whole-genome sequencing with...

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Literature Corpus work
19a6de5e-c193-59f7-85ea-feb83e77b36d
DOI
10.1101/2020.02.14.943365
Open publication

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Rv1985c-Driven Transcriptional Network Rewiring Underlies Lineage-Specific Phenotypes in <i>Mycobacterium tuberculosis</i>DOI 10.1101/2020.02.14.943365
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