Article
The Mycobacterium DosR regulon structure and diversity revealed by comparative genomic analysis.
Journal of cellular biochemistry - 1 Jan 2013
Chen Tian, He Liming, Deng Wanyan, Xie Jianping
Abstract excerpt
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), which claims approximately two million people annually, remains a global health concern. The non-replicating or dormancy like state of this pathogen which is impervious to anti-tuberculosis drugs is widely recognized as the culprit for this scenario. The dormancy survival regulator (DosR) regulon, composed of 48 co-regulated genes, is held as...
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