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Exposure of <i>Mycobacterium tuberculosis</i> to human alveolar lining fluid shows temporal and strain-specific adaptation to the lung environment

2023-09-28

Abstract excerpt

<h4>ABSTRACT</h4> Upon infection, Mycobacterium tuberculosis ( M.tb ) reaches the alveolar space and comes in close contact with human alveolar lining fluid (ALF) for an uncertain period of time prior to its encounter with alveolar cells. We showed that homeostatic ALF hydrolytic enzymes modify the M.tb cell envelope, driving M.tb -host cell interactions. Still, the contribution of ALF during M.tb infection...

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Literature Corpus work
60996d02-a041-5a3a-8cbf-a3992dc333f1
DOI
10.1101/2023.09.27.559381
Open publication

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Exposure of <i>Mycobacterium tuberculosis</i> to human alveolar lining fluid shows temporal and strain-specific adaptation to the lung environmentDOI 10.1101/2023.09.27.559381
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