Article

The Aquarius/EMB-4 helicase licenses co-transcriptional gene silencing

2016-12-05

Abstract excerpt

<h4>SUMMARY</h4> Small RNAs (sRNAs) play an ancient role in genome defence against transposable elements. In animals, plants and fungi small RNAs guide Argonaute proteins to nascent RNA transcripts to induce co-transcriptional gene silencing. In animals the link between small RNA pathways and the transcriptional machinery remains unclear. Here we show that the Caenorhabditis elegans germline Argonaute HRDE-1 phy...

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Literature Corpus work: 1960d7f5-354b-57b4-83ae-9b705facfdae
DOI: 10.1101/089763

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