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<i>Caenorhabditis elegans</i> ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons

2019-10-31

Abstract excerpt

<h4>ABSTRACT</h4> Endogenous retroviruses and LTR retrotransposons are mobile genetic elements that are closely related to retroviruses. Desilenced endogenous retroviruses are associated with human autoimmune disorders and neurodegenerative diseases. C. elegans and related Caenorhabdites contain LTR retrotransposons and, as described here, numerous integrated viral genes including viral envelope genes that are...

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Literature Corpus work
a3bb066f-c774-56bf-96f5-8db320b2b1b1
DOI
10.1101/825315
Open publication

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