Article

A PML–PPAR-δ Pathway for Fatty Acid Oxidation Regulates Hematopoietic Stem Cell Maintenance Through the Control of Asymmetric Division.

2012-11-16

Abstract excerpt

Abstract Abstract 2327 Stem-cell function is an exquisitely regulated process. Thus far, the contribution of metabolic cues to stem-cell function has not been well understood. Here we have established a new assay for the assessment of asymmetric division in hematopoietic stem cells (HSCs), and identify a previously unknown promyelocytic leukemia (PML)–peroxisome proliferator-activated receptor δ (PPAR-δ)–fatty-aci...

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Literature Corpus work: 192f1b74-d16f-5cb5-9dfc-b1eb2bbf9c3b
DOI: 10.1182/blood.v120.21.2327.2327

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