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Symmetric and asymmetric activation of hematopoietic stem cells

26 Feb 2021

Abstract excerpt

PURPOSE OF REVIEW: Hematopoietic stem cells (HSCs) are in an inactive quiescent state for most of their life. To replenish the blood system in homeostasis and after injury, they activate and divide. HSC daughter cells must then decide whether to return to quiescence and metabolic inactivity or to activate further to proliferate and differentiate and replenish lost blood cells. Although the regulation of HSC...

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PMID: 34059600
DOI: 10.1097/moh.0000000000000644

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