Article

ZC3HC1 has many functions distinct from TPR and is dispensable for TPR localisation to the nuclear basket

2025-11-24

Abstract excerpt

<h4>Background: </h4> The nuclear basket is a ‘fishtrap’-like structure on the nucleoplasmic face of the nuclear pore complex which has been implicated in diverse functions including RNA export, heterochromatin organisation, and mitosis. Recently, a novel component of the nuclear basket, ZC3HC1, has been described. The localisation of ZC3HC1 to nuclear pores has been reported to occur reciprocally with TPR, a majo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 18d5b02e-4ab1-5911-a6e1-0b17dc2e0078
DOI: 10.12688/wellcomeopenres.23711.2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

ZC3HC1 has many functions distinct from TPR and is dispensable for TPR localisation to the nuclear basketDOI 10.12688/wellcomeopenres.23711.2Read

Silencing nuclear pore protein Tpr elicits a senescent-like phenotype in cancer cells.Semantic proximity Read

ZC3H4 restricts non-coding transcription in human cellsSemantic proximity Read

Fraying at the edge mouse models of diseases resulting from defects at the nuclear periphery.Semantic proximity Read

CXIP4 depletion causes early lethality and pre-mRNA missplicing in ArabidopsisSemantic proximity Read

FAM172A controls the nuclear import and alternative splicing function of AGO2Semantic proximity Read

ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatinSemantic proximity Read

Ablation of ZC3H11A causes early embryonic lethality and dysregulation of metabolic processesSemantic proximity Read

Replication stress conferred by POT1 dysfunction promotes telomere relocalization to the nuclear pore.Semantic proximity Read

Live-cell imaging of circadian clock protein dynamics in CRISPR-generated knock-in cellsSemantic proximity Read

The role of nuclear pores in gene regulation, development and diseaseSemantic proximity Read

Nuclear lamin A/C phosphorylation by loss of Androgen Receptor is a global determinant of cancer-associated fibroblast activationSemantic proximity Read

Keratin 17 regulates nuclear morphology and chromatin organizationSemantic proximity Read