Article

ZC3H4 restricts non-coding transcription in human cells

2021-02-11

Abstract excerpt

<h4>SUMMARY</h4> The human genome encodes thousands of non-coding RNAs. Many of these terminate early and are then rapidly degraded, but how their transcription is restricted is poorly understood. In a screen for protein-coding gene termination factors, we identified ZC3H4. However, its depletion causes upregulation and extension of hundreds of unstable transcripts, particularly antisense RNAs and those transcrib...

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Literature Corpus work: 5d31f584-497a-575c-975b-3606b0222ec4
DOI: 10.1101/2021.02.10.430684

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