Article

FAM172A controls the nuclear import and alternative splicing function of AGO2

2022-03-05

Abstract excerpt

The poorly characterized protein FAM172A is mutated in some individuals affected by a disorder of neural crest development called CHARGE syndrome. We also know that FAM172A can interact with the main CHARGE syndrome-associated protein CHD7 and the small RNA-binding protein AGO2 at the chromatin-spliceosome interface. Focusing on this intriguing FAM172A-AGO2 interaction, we now report that FAM172A is one of the lon...

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Literature Corpus work: 21d9b859-7c28-506d-a5f1-edd30499d1a2
DOI: 10.1101/2022.03.04.482948

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