Article

Ablation of ZC3H11A causes early embryonic lethality and dysregulation of metabolic processes

2022-09-16

Abstract excerpt

ZC3H11A is a stress-induced mRNA binding protein required for efficient growth of nuclear-replicating viruses, while being dispensable for the viability of cultured human cells. The cellular functions of ZC3H11A during embryo development are unknown. Here we report the generation and phenotypic characterization of Zc3h11a knock-out mice. Heterozygous null Zc3h11a mice were born at the expected frequency without...

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Literature Corpus work: 4afb4cde-385d-5a97-8f30-334d37266a4c
DOI: 10.1101/2022.09.14.508037

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