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Article

Single-cell and multi-layer analysis identifies state-restricted stromal remodeling in steroid-associated osteonecrosis of the femoral head

2026-07-04

Abstract excerpt

<title>Abstract</title> <p>Background Steroid-associated osteonecrosis of the femoral head is characterized by marrow stromal remodeling and adipogenic imbalance, but the configuration of stress-adaptation coupling within disease-associated stromal states remains unclear. Methods We applied a multi-layer analytical strategy to characterize stromal remodeling in steroid-associated osteonecrosis of the femoral he...

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Literature Corpus work
18534e9b-bfc8-5aa3-9378-3b0f0f18ccf5
DOI
10.21203/rs.3.rs-9712673/v1
Open publication

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Single-cell and multi-layer analysis identifies state-restricted stromal remodeling in steroid-associated osteonecrosis of the femoral headDOI 10.21203/rs.3.rs-9712673/v1
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