Article

ECM-remodeling perivascular stromal state associates with osteoclast functional state in breast cancer bone metastasis

2026-08-25

Abstract excerpt

<title>Abstract</title> <p>Background Bone metastasis is a major cause of morbidity and disease progression in breast cancer, but the cellular sources of patient-level metastatic risk programs remain incompletely defined. We aimed to connect bulk transcriptomic risk signals with specific microenvironmental cell states in breast cancer bone metastasis. Methods We integrated three public bulk transcriptomic cohor...

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Literature Corpus work: 4079e1e7-45bf-58ef-935a-b6af225f8e38
DOI: 10.21203/rs.3.rs-10575957/v1

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ECM-remodeling perivascular stromal state associates with osteoclast functional state in breast cancer bone metastasisDOI 10.21203/rs.3.rs-10575957/v1Read

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