Article

Tissue-intrinsic γδ T cells critically regulate Tissue-Resident Memory CD8 T cells

2022-01-21

Abstract excerpt

<h4>Summary</h4> Because Tissue-Resident Memory T (T RM ) cells contribute critically to body-surface immunoprotection and/or immunopathology in multiple settings, their regulation is biologically and clinically important. Interestingly, T RM commonly develop in epithelia part-shaped by innate-like lymphocytes that become tissue-intrinsic during development. Here we show that polyclonal T RM cells induced by a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e476d119-c45c-5237-bc9c-1d0f66afb495
DOI: 10.1101/2022.01.19.476598

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Tissue-intrinsic γδ T cells critically regulate Tissue-Resident Memory CD8 T cellsDOI 10.1101/2022.01.19.476598Read

Functional heterogeneity of human skin-resident memory T cells in health and disease.Semantic proximity Read

T cell receptor γδ is a critical, real-time determinant of unique tissue surveillance mechanismsSemantic proximity Read

A feedback control for restraining autoimmune γδ T cells: reprogramming into ILC1sSemantic proximity Read

Persistence of CD8+ skin-resident memory T cells in mice requires TCR signalingSemantic proximity Read

Comparing Mouse and Human Tissue-Resident γδ T CellsSemantic proximity Read

Lymph node resident memory T cells retain effector capabilities by evading lung resident memory dysfunctionSemantic proximity Read

Tissue-resident memory T cells in tissue homeostasis, persistent infection, and cancer surveillance.Semantic proximity Read

Dermal γδ T cells – What have we learned?Semantic proximity Read

Cutting Edge: Identification of a Motile IL-17–Producing γδ T Cell Population in the DermisSemantic proximity Read

Tissue‐Resident Memory CD8+ T Cells: Differentiation, Phenotypic Heterogeneity, Biological Function, Disease, and TherapySemantic proximity Read

Bystander memory-phenotype conventional CD4 <sup>+</sup> T cells exacerbating autoimmune neuroinflammationSemantic proximity Read

Tertiary lymphoid structures support the development of allergen-specific progenitor CD4+ T cellsSemantic proximity Read