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Simultaneous discovery of candidate imprinted genes and Imprinting Control Regions in the mouse genome

2019-09-24

Abstract excerpt

<h4>ABSTRACT</h4> In mammals, parent-of-origin-specific gene expression is regulated by specific genomic DNA segments known as Imprinting Control Regions (ICRs) and germline Differentially Methylated Regions (gDMRs). In the mouse genome, the known ICRs/gDMRs often include clusters of a set of composite-DNA-elements known as ZFBS-morph overlaps. These elements consist of the ZFP57 binding site (ZFBS) overlapping a...

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Literature Corpus work
18275a49-ef2a-5a02-8913-315ddb6702da
DOI
10.1101/780551
Open publication

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