Article

Epigenetic control of SOX9 gene by the histone acetyltransferase P300 in human Sertoli cells

2024-06-01

Abstract excerpt

Background The transcription factor SOX9 is a key regulator of male sexual development and Sertoli cell differentiation. Altered S OX9 expression has been implicated in the pathogenesis of disorders of sexual development (DSD) in mammals. However, limited information exists regarding the epigenetic mechanisms governing its transcriptional control during sexual development. Methods This study employed real-time PCR...

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Literature Corpus work: 17c35bb1-47c1-5522-9313-d64e1ed9f0e5
DOI: 10.1016/j.heliyon.2024.e33173

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