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Article

Regulation of the Orphan Nuclear Receptor Steroidogenic Factor 1 by Sox Proteins

1 Mar 2002

Abstract excerpt

Steroidogenic factor 1 (SF-1) is an essential factor in endocrine proliferation and gene expression. Despite the fact that SF-1 expression is restricted to specialized cells within the endocrine system, the only identified regulatory factors of SF-1 are the ubiquitously expressed E-box proteins (upstream stimulatory factors 1 and 2). Sequence examination of the SF-1 proximal promoter revealed a conserved site of...

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PMID: 11875113
DOI: 10.1210/mend.16.3.0782

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