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Article

SOX9 and the many facets of its regulation in the chondrocyte lineage

29 Apr 2016

Abstract excerpt

SOX9 is a pivotal transcription factor in developing and adult cartilage. Its gene is expressed from the multipotent skeletal progenitor stage and is active throughout chondrocyte differentiation. While it is repressed in hypertrophic chondrocytes in cartilage growth plates, it remains expressed throughout life in permanent chondrocytes of healthy articular cartilage. SOX9 is required for chondrogenesis: it...

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Identifiers

PMID: 27128146
DOI: 10.1080/03008207.2016.1183667

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